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Table 1 A comparison of the risk factors for RSV hospitalised and non hospitalised infants in the FLIP and Munich studies

From: A predictive model for respiratory syncytial virus (RSV) hospitalisation of premature infants born at 33–35 weeks of gestational age, based on data from the Spanish FLIP study

  FLIP [9] Munich [8]
  Hospitalised (n = 186) Non-hospitalised (n = 367) Odds Ratio
(CI 95%)
P-value* Hospitalised (n = 20) Non-hospitalised (n = 357) Odds Ratio
(CI 95%)
P-value*
Birth ± 10 weeks of start of season 136 (73.1%) 145 (39.5%) 4.16 (2.78–6.23) < 0.0001 12 (60.0%) 148 (41.5%) 2.12 (0.77–6.12) 0.1101
Birth weight, kg a 2.20 (0.38) 2.12 (0.42) - 0.0419 2.14 (0.38) 2.11 (0.39) - 0.7526
Breast fed ≤ 2 months or not § 146 (78.5%) 206 (56.1%) 2.85 (1.87–4.40) < 0.0001 18 (90.0%) 286 (80.1%) 2.23 (0.51–20.3) 0.3887
Number of siblings ≥ 2 years 1 (0–1) 0 (0–1) - < 0.0001 1 (0–2) 0 (0–1) - 0.0172
Number of family with atopy § 0 (0-0) 0 (0-0) - 0.0117 12 (60.0%) 175 (49.0%) 1.56 (0.57–4.51) 0.3671
Male gender 117 (62.9%) 199 (54.2%) 1.43 (0.98–2.09) 0.0513 18 (90.0%) 177 (49.6%) 9.15 (2.13–82.14) 0.0003
Number of family with wheeze 0 (0–1) 0 (0-0) - 0.0004 - - - -
Gestational age         
33 weeks 49 (26.3%) 77 (21.0%) 1.34 (0.87–2.07) 0.1554 4 (20.0%) 119 (33.3%) 0.50 (0.12–1.60) 0.3265
34 weeks 60 (32.3%) 139 (37.9%) 0.78 (0.53–1.15) 0.1935 11 (55.0%) 172 (48.2%) 1.31 (0.48–3.68) 0.648
35 weeks 77 (41.4%) 151 (41.1%) 1.01 (0.69–1.47) 0.9544 5 (25.0%) 66 (18.5%) 1.47 (0.40–4.44) 0.5544
Number of regular carers 2 (1–2) 2 (1–2) - 0.0377 - - - -
Furred pets at home 46 (24.7%) 68 (18.5%) 1.44 (0.92–2.25) 0.0885 - - - -
Educational level of parents         
No school 7 (3.8%) 4 (1.1%) 3.54 (0.89–16.71) 0.0711 - - - -
Primary 53 (28.5%) 84 (22.9%) 1.34 (0.88–2.04) 0.1491 - - - -
High school 78 (41.9%) 156 (42.5%) 0.98 (0.67–1.42) 0.8978 - - - -
University 48 (25.8%) 123 (33.5%) 0.69 (0.45–1.04) 0.0639 - - - -
Number of births in delivery 1 (1–2) 1 (1–2) - 0.531 1 (1-1) 1 (1–2) - 0.1675
Smoking during pregnancyb 56 (30.3%) 79 (21.5%) 1.58 (1.03–2.40) 0.0241 - - - -
Number of smokers around infantc 1 (0–2) 1 (0–2) - 0.062 0 (0–1) 0 (0–1) - 0.9479
Number of family with asthma 0 (0-0) 0 (0-0) - 0.1114 - - - -
  1. The 8 variables used in the final model are shown in italics. All variables were used in the initial 15 variable model
  2. † Mean (standard deviation), median (P25-P75), number (%)
  3. * Student's t test, Mann-Whitney U test, χ2 test
  4. §Recorded as breast fed yes/no and atopy yes/no for Munich
  5. a 2 missing values for FLIP, 5 missing values for Munich
  6. b 1 missing value for FLIP
  7. c 2 missing values for Munich