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Table 1 A comparison of the risk factors for RSV hospitalised and non hospitalised infants in the FLIP and Munich studies

From: A predictive model for respiratory syncytial virus (RSV) hospitalisation of premature infants born at 33–35 weeks of gestational age, based on data from the Spanish FLIP study

 

FLIP [9]

Munich [8]

 

Hospitalised (n = 186)

Non-hospitalised (n = 367)

Odds Ratio

(CI 95%)

P-value*

Hospitalised (n = 20)

Non-hospitalised (n = 357)

Odds Ratio

(CI 95%)

P-value*

Birth ± 10 weeks of start of season

136 (73.1%)

145 (39.5%)

4.16 (2.78–6.23)

< 0.0001

12 (60.0%)

148 (41.5%)

2.12 (0.77–6.12)

0.1101

Birth weight, kg a

2.20 (0.38)

2.12 (0.42)

-

0.0419

2.14 (0.38)

2.11 (0.39)

-

0.7526

Breast fed ≤ 2 months or not §

146 (78.5%)

206 (56.1%)

2.85 (1.87–4.40)

< 0.0001

18 (90.0%)

286 (80.1%)

2.23 (0.51–20.3)

0.3887

Number of siblings ≥ 2 years

1 (0–1)

0 (0–1)

-

< 0.0001

1 (0–2)

0 (0–1)

-

0.0172

Number of family with atopy §

0 (0-0)

0 (0-0)

-

0.0117

12 (60.0%)

175 (49.0%)

1.56 (0.57–4.51)

0.3671

Male gender

117 (62.9%)

199 (54.2%)

1.43 (0.98–2.09)

0.0513

18 (90.0%)

177 (49.6%)

9.15 (2.13–82.14)

0.0003

Number of family with wheeze

0 (0–1)

0 (0-0)

-

0.0004

-

-

-

-

Gestational age

        

33 weeks

49 (26.3%)

77 (21.0%)

1.34 (0.87–2.07)

0.1554

4 (20.0%)

119 (33.3%)

0.50 (0.12–1.60)

0.3265

34 weeks

60 (32.3%)

139 (37.9%)

0.78 (0.53–1.15)

0.1935

11 (55.0%)

172 (48.2%)

1.31 (0.48–3.68)

0.648

35 weeks

77 (41.4%)

151 (41.1%)

1.01 (0.69–1.47)

0.9544

5 (25.0%)

66 (18.5%)

1.47 (0.40–4.44)

0.5544

Number of regular carers

2 (1–2)

2 (1–2)

-

0.0377

-

-

-

-

Furred pets at home

46 (24.7%)

68 (18.5%)

1.44 (0.92–2.25)

0.0885

-

-

-

-

Educational level of parents

        

No school

7 (3.8%)

4 (1.1%)

3.54 (0.89–16.71)

0.0711

-

-

-

-

Primary

53 (28.5%)

84 (22.9%)

1.34 (0.88–2.04)

0.1491

-

-

-

-

High school

78 (41.9%)

156 (42.5%)

0.98 (0.67–1.42)

0.8978

-

-

-

-

University

48 (25.8%)

123 (33.5%)

0.69 (0.45–1.04)

0.0639

-

-

-

-

Number of births in delivery

1 (1–2)

1 (1–2)

-

0.531

1 (1-1)

1 (1–2)

-

0.1675

Smoking during pregnancyb

56 (30.3%)

79 (21.5%)

1.58 (1.03–2.40)

0.0241

-

-

-

-

Number of smokers around infantc

1 (0–2)

1 (0–2)

-

0.062

0 (0–1)

0 (0–1)

-

0.9479

Number of family with asthma

0 (0-0)

0 (0-0)

-

0.1114

-

-

-

-

  1. The 8 variables used in the final model are shown in italics. All variables were used in the initial 15 variable model
  2. † Mean (standard deviation), median (P25-P75), number (%)
  3. * Student's t test, Mann-Whitney U test, χ2 test
  4. §Recorded as breast fed yes/no and atopy yes/no for Munich
  5. a 2 missing values for FLIP, 5 missing values for Munich
  6. b 1 missing value for FLIP
  7. c 2 missing values for Munich