FLIP [9] | Munich [8] | |||||||
---|---|---|---|---|---|---|---|---|
Hospitalised (n = 186) | Non-hospitalised (n = 367) | Odds Ratio (CI 95%) | P-value* | Hospitalised (n = 20) | Non-hospitalised (n = 357) | Odds Ratio (CI 95%) | P-value* | |
Birth ± 10 weeks of start of season | 136 (73.1%) | 145 (39.5%) | 4.16 (2.78–6.23) | < 0.0001 | 12 (60.0%) | 148 (41.5%) | 2.12 (0.77–6.12) | 0.1101 |
Birth weight, kg a | 2.20 (0.38) | 2.12 (0.42) | - | 0.0419 | 2.14 (0.38) | 2.11 (0.39) | - | 0.7526 |
Breast fed ≤ 2 months or not § | 146 (78.5%) | 206 (56.1%) | 2.85 (1.87–4.40) | < 0.0001 | 18 (90.0%) | 286 (80.1%) | 2.23 (0.51–20.3) | 0.3887 |
Number of siblings ≥ 2 years | 1 (0–1) | 0 (0–1) | - | < 0.0001 | 1 (0–2) | 0 (0–1) | - | 0.0172 |
Number of family with atopy § | 0 (0-0) | 0 (0-0) | - | 0.0117 | 12 (60.0%) | 175 (49.0%) | 1.56 (0.57–4.51) | 0.3671 |
Male gender | 117 (62.9%) | 199 (54.2%) | 1.43 (0.98–2.09) | 0.0513 | 18 (90.0%) | 177 (49.6%) | 9.15 (2.13–82.14) | 0.0003 |
Number of family with wheeze | 0 (0–1) | 0 (0-0) | - | 0.0004 | - | - | - | - |
Gestational age | ||||||||
33 weeks | 49 (26.3%) | 77 (21.0%) | 1.34 (0.87–2.07) | 0.1554 | 4 (20.0%) | 119 (33.3%) | 0.50 (0.12–1.60) | 0.3265 |
34 weeks | 60 (32.3%) | 139 (37.9%) | 0.78 (0.53–1.15) | 0.1935 | 11 (55.0%) | 172 (48.2%) | 1.31 (0.48–3.68) | 0.648 |
35 weeks | 77 (41.4%) | 151 (41.1%) | 1.01 (0.69–1.47) | 0.9544 | 5 (25.0%) | 66 (18.5%) | 1.47 (0.40–4.44) | 0.5544 |
Number of regular carers | 2 (1–2) | 2 (1–2) | - | 0.0377 | - | - | - | - |
Furred pets at home | 46 (24.7%) | 68 (18.5%) | 1.44 (0.92–2.25) | 0.0885 | - | - | - | - |
Educational level of parents | ||||||||
No school | 7 (3.8%) | 4 (1.1%) | 3.54 (0.89–16.71) | 0.0711 | - | - | - | - |
Primary | 53 (28.5%) | 84 (22.9%) | 1.34 (0.88–2.04) | 0.1491 | - | - | - | - |
High school | 78 (41.9%) | 156 (42.5%) | 0.98 (0.67–1.42) | 0.8978 | - | - | - | - |
University | 48 (25.8%) | 123 (33.5%) | 0.69 (0.45–1.04) | 0.0639 | - | - | - | - |
Number of births in delivery | 1 (1–2) | 1 (1–2) | - | 0.531 | 1 (1-1) | 1 (1–2) | - | 0.1675 |
Smoking during pregnancyb | 56 (30.3%) | 79 (21.5%) | 1.58 (1.03–2.40) | 0.0241 | - | - | - | - |
Number of smokers around infantc | 1 (0–2) | 1 (0–2) | - | 0.062 | 0 (0–1) | 0 (0–1) | - | 0.9479 |
Number of family with asthma | 0 (0-0) | 0 (0-0) | - | 0.1114 | - | - | - | - |