Figure 1From: An intranasal selective antisense oligonucleotide impairs lung cyclooxygenase-2 production and improves inflammation, but worsens airway function, in house dust mite sensitive miceSensitization protocol and antisense oligonucleotide (ASO) administration. Oligonucleotide was administered intranasally one hour before house dust mite (HDM). Twenty-four hours after the last challenge, pulmonary function was assessed by unrestrained whole body plethysmography. Animals were sacrificed the following day and samples were taken.Back to article page