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Figure 4 | Respiratory Research

Figure 4

From: Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex

Figure 4

Effect of other proteinases on SLPI concentration in A549 cells. A549 cells were cultured with varying concentrations of each proteinase for 24 h. The concentration of SLPI, expressed as a percentage of the concentration in serum free media, is shown on the y axis with the SEM represented by error bars. P indicates that the cells exhibited morphological changes of partial detachment, 'rounding up' and losing attachment to each other but remaining adherent to the culture plate, whilst D indicates that the cells detached completely from the culture plate. The effect on SLPI concentration was only independent of cell morphology for CG. Values given are mean ± SEM for at least 3 experiments.

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