MAPK blockers inhibit SR mediated phagocytosis. Adherent GM-MØ were pretreated with inhibitors of either JNK (A) or MEK (B) before incubation with fluorescent latex beads. Cells were analyzed for the percent internalization of bound beads. Bars represent the means of five (A) or six (B) donors +/- the standard deviation. For each donor, three fields from each of three replicate wells were analyzed. **p < 0.001 when compared to either the control, JNK control or DMSO conditions.