Protein kinase C blockers inhibit SR mediated phagocytosis. Adherent GM-MØ were pretreated with either staurosporine (A), chelerythryine chloride or Gö 6976 (B) before incubation with fluorescent latex beads. Cells were analyzed for the percent internalization of bound beads. Bars represent the means of five (A) or three (B) donors +/- the standard deviation. For each donor, three fields from each of three replicate wells were analyzed. *p < 0.01 and **p < 0.001 when compared to either the control or DMSO conditions.