Comparisons of ENO and ECO across mouse strains. A. Exhaled NO (ENO) with airway inflammation, expressed as fold change as compared to ENO in respective-strain naïve mice. *P < 0.05 vs. respective-strain naïve mice controls; +P < 0.05 MKK3-/- vs. MKK3-sufficient (C57/C129) controls, and P < 0.05 NOS-2-/- vs. NOS-3-/- mice. Values are means ± SE; strain(n) = C57Bl6(8), IL-10-/-(12), A/J(12), MKK3-/-(11), C57/C129(6), JNK1-/-(4), NOS-2-/-(8), NOS-3-/-(14). B. Changes in exhaled CO (ECO) with induction of airway inflammation, expressed as fold change as compared to ECO in respective-strain mice. Values are means ± SE, with significance and n as in Panel A.