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Table 1 Effect of Olmesartan Medoxomil on cell components in bronchoalveolar lavage fluid

From: Angiotensin II type 2 receptor antagonist reduces bleomycin-induced pulmonary fibrosis in mice

   

Cell differentiation (× 105/ml)

  

Total cell number (× 105/ml)

Mac

Lym

Neu

Day 7

     
 

BLM (n = 8)

182.4 ± 7.1

67.6 ± 4.0

99.9 ± 5.6

14.9 ± 3.0

 

BLM + OL (n = 8)

127.8 ± 13.4 **

55.9 ± 6.2

64.5 ± 7.8 **

7.4 ± 1.2 *

 

OL (n = 8)

7.8 ± 2.5

6.4 ± 2.1

1.0 ± 0.3

0.4 ± 0.3

Day 14

     
 

BLM (n = 8)

163.7 ± 15.6

87.6 ± 8.1

61.9 ± 10.0

2.5 ± 0.8

 

BLM + OL (n = 8)

108.5 ± 34.3 *

52.6 ± 16.6 **

37.6 ± 16.8 *

1.5 ± 0.7

 

OL (n = 8)

15.4 ± 2.6

12.9 ± 3.0

0.2 ± 0.1

0.1 ± 0.1

  1. Mac; Macrophages, Lym; lymphocytes, Neu; neutrophils, BLM; bleomycin, OL; olmesartan medoxomil
  2. Values are expressed as mean ± SEM.
  3. *p < 0.05, **p < 0.01 as compared to the BLM group.