Skip to main content
Figure 5 | Respiratory Research

Figure 5

From: Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone

Figure 5

Nuclear DNA fragmentation ofL. pneumophila-infected A549 cells detected by the TUNEL method. TUNEL-positive A549 cell numbers with each stimulus are presented. Cells were observed with a confocal laser scanning microscopy. More than 500 cells were counted from 10 randomized high-power fields, and TUNEL-positive cells were expressed as a ratio per total number of cells. Symbols: ▫, virulent strain AA100jm; ▪, avirulent strain dotO mutant. Data are mean ± SD of three different experiments. * P < 0.05.

Back to article page