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Figure 4 | Respiratory Research

Figure 4

From: Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisolone

Figure 4

Nuclear DNA fragmentation ofL. pneumophila-infected A549 cells detected by the TUNEL method. MOI dose-response relationship of nuclear DNA fragmentations 2 days after infection with the virulent AA100jm strain (A-D) and the avirulent dotO mutant strain (E-H). Nuclear DNA fragmentation of cells 2 days after exposure to 30 μM mitomycin C (I) and with no treatment (control) (J). Cells were observed with a confocal laser scanning microscopy (all 200 ×). The nuclear DNA fragmentation is shown in green (FITC staining), and A549 cell nuclei in red (PI staining).

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Respiratory Research

ISSN: 1465-993X

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