Figure 11From: Legionella pneumophila infection induces programmed cell death, caspase activation, and release of high-mobility group box 1 protein in A549 alveolar epithelial cells: inhibition by methyl prednisoloneInfluence of methyl prednisolone on HMGB1 release fromL. pneumophila-infected A549 cells. Cells were pre-treated with and without methyl prednisolone (53.4 μM) for one day, and subsequently infected with the virulent AA100jm strain of L. pneumophila. After another day, HMGB1 release was measured in cell supernatants. Symbols: ▫, without methyl prednisolone; ▪, with methyl prednisolone. Data are mean ± SD of three different experiments. * P < 0.05.Back to article page