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Table 5 Weighted GSMA for total serum IgE (729 pedigrees, n = 3,224)

From: Meta-analysis of genome-wide linkage studies of asthma and related traits

     

PROBABILITY

BIN (a)

GENETIC LOCUS (b)

DIST. (cM) (c)

PHYS POS. (KB) (d)

SUMMED RANK (SR)

p(SR)

p(OR)

2

1p36.23-p35.3

20.61–54.30

9332 – 24723

476.251

0.01171

0.41867

7

1q23.3-q31.1

170.84–201.58

159125–185232

450.659

0.03099

0.14664

39

5q11.2-q14.3

64.14–97.82

55758–88765

450.303

0.03127

0.06031

41

5q23.2-q34

131.48–164.19

123774–162087

464.611

0.01890

0.40276

43

6pter-p22.3

0.00–32.62

pter-16854

448.903

0.03276

0.02583

44

6p22.3-p21.1

32.62–65.14

16854–43207

479.723

0.00999

0.71984

50

7p21.1-p14.1

29.28–59.93

19430–40230

454.706

0.02708

0.41494

76

11q13.3-q22.3

72.82–98.98

70185–103732

453.763

0.02792

0.22926

  1. Chromosomal regions with a p(SR) or p(OR) < 0.05 are shown. aBin number from GSMA (1–120 inclusive). bCytogenetic band (Taken from April 2002 Genome Browser, UCSC). cGenetic distance in Marshfield cM (not cumulative). dPhysical position in kilobase pairs (Taken from December 2006 UniSTS, NCBI/Genome Browser, UCSC). *p < 0.000417 = Genome wide significance for linkage, p < 0.0083 = Suggestive for linkage [5].