Skip to main content

Table 5 Weighted GSMA for total serum IgE (729 pedigrees, n = 3,224)

From: Meta-analysis of genome-wide linkage studies of asthma and related traits

      PROBABILITY
BIN (a) GENETIC LOCUS (b) DIST. (cM) (c) PHYS POS. (KB) (d) SUMMED RANK (SR) p(SR) p(OR)
2 1p36.23-p35.3 20.61–54.30 9332 – 24723 476.251 0.01171 0.41867
7 1q23.3-q31.1 170.84–201.58 159125–185232 450.659 0.03099 0.14664
39 5q11.2-q14.3 64.14–97.82 55758–88765 450.303 0.03127 0.06031
41 5q23.2-q34 131.48–164.19 123774–162087 464.611 0.01890 0.40276
43 6pter-p22.3 0.00–32.62 pter-16854 448.903 0.03276 0.02583
44 6p22.3-p21.1 32.62–65.14 16854–43207 479.723 0.00999 0.71984
50 7p21.1-p14.1 29.28–59.93 19430–40230 454.706 0.02708 0.41494
76 11q13.3-q22.3 72.82–98.98 70185–103732 453.763 0.02792 0.22926
  1. Chromosomal regions with a p(SR) or p(OR) < 0.05 are shown. aBin number from GSMA (1–120 inclusive). bCytogenetic band (Taken from April 2002 Genome Browser, UCSC). cGenetic distance in Marshfield cM (not cumulative). dPhysical position in kilobase pairs (Taken from December 2006 UniSTS, NCBI/Genome Browser, UCSC). *p < 0.000417 = Genome wide significance for linkage, p < 0.0083 = Suggestive for linkage [5].