Skip to main content

Table 4 Weighted GSMA for skin prick test response (1,093 pedigrees, n = 4,746)

From: Meta-analysis of genome-wide linkage studies of asthma and related traits

     

PROBABILITY

BIN (a)

GENETIC LOCUS (b)

DIST. (cM) (c)

PHYS POS. (KB) (d)

SUMMED RANK (SR)

p(SR)

p(OR)

6

1p13.3-q23.3

142.24–170.84

110103–159125

541.271

0.02081

0.22906

23

3p22.1-p14.1

63.12–88.60

38845–64182

513.869

0.04488

0.06344

24

3p14.1-q12.3

88.60–117.76

64182–103187

591.392

0.00298*

0.00450

25

3q12.3-q22.1

117.76–146.60

103187–134474

614.373

0.00084*

0.00406

45

6p21.1-q15

65.14–99.01

43207–90985

521.717

0.03654

0.12598

46

6q15-q23.2

99.01–131.07

90985–132584

525.276

0.03318

0.18839

77

11q22.3-q24.1

98.98–123.00

103732–122977

515.746

0.04276

0.11460

102

17p12-q21.33

25.14–63.62

11325–39726

624.777

0.00043*

0.05044

103

17q21.33-q24.3

63.62–93.98

39726–66600

511.187

0.04799

0.03824

108

18q22.1-qter

96.48–126.00

60025-qter

209.839

0.96132

0.03480

118

21q21.3-qter

25.26–57.77

27903-qter

528.536

0.03029

0.28738

  1. Chromosomal regions with a p(SR) or p(OR) < 0.05 are shown. aBin number from GSMA (1–120 inclusive). bCytogenetic band (Taken from April 2002 Genome Browser, UCSC). cGenetic distance in Marshfield cM (not cumulative). dPhysical position in kilobase pairs (Taken from December 2006 UniSTS, NCBI/Genome Browser, UCSC). *p < 0.000417 = Genome wide significance for linkage, p < 0.0083 = Suggestive for linkage [5].