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Table 4 Weighted GSMA for skin prick test response (1,093 pedigrees, n = 4,746)

From: Meta-analysis of genome-wide linkage studies of asthma and related traits

      PROBABILITY
BIN (a) GENETIC LOCUS (b) DIST. (cM) (c) PHYS POS. (KB) (d) SUMMED RANK (SR) p(SR) p(OR)
6 1p13.3-q23.3 142.24–170.84 110103–159125 541.271 0.02081 0.22906
23 3p22.1-p14.1 63.12–88.60 38845–64182 513.869 0.04488 0.06344
24 3p14.1-q12.3 88.60–117.76 64182–103187 591.392 0.00298* 0.00450
25 3q12.3-q22.1 117.76–146.60 103187–134474 614.373 0.00084* 0.00406
45 6p21.1-q15 65.14–99.01 43207–90985 521.717 0.03654 0.12598
46 6q15-q23.2 99.01–131.07 90985–132584 525.276 0.03318 0.18839
77 11q22.3-q24.1 98.98–123.00 103732–122977 515.746 0.04276 0.11460
102 17p12-q21.33 25.14–63.62 11325–39726 624.777 0.00043* 0.05044
103 17q21.33-q24.3 63.62–93.98 39726–66600 511.187 0.04799 0.03824
108 18q22.1-qter 96.48–126.00 60025-qter 209.839 0.96132 0.03480
118 21q21.3-qter 25.26–57.77 27903-qter 528.536 0.03029 0.28738
  1. Chromosomal regions with a p(SR) or p(OR) < 0.05 are shown. aBin number from GSMA (1–120 inclusive). bCytogenetic band (Taken from April 2002 Genome Browser, UCSC). cGenetic distance in Marshfield cM (not cumulative). dPhysical position in kilobase pairs (Taken from December 2006 UniSTS, NCBI/Genome Browser, UCSC). *p < 0.000417 = Genome wide significance for linkage, p < 0.0083 = Suggestive for linkage [5].