Skip to main content

Table 2 Weighted GSMA for Asthma (1,267 pedigrees, n = 5,832)

From: Meta-analysis of genome-wide linkage studies of asthma and related traits

      PROBABILITY
BIN (a) GENETIC LOCUS (b) DISTANCE (cM) (c) PHYSICAL POSITION (KB) (d) SUMMED RANK (SR) p(SR) p(OR)
1 1pter-p36.23 0.00–20.61 pter-9332 376.576 0.68121 0.03775
5 1p31.1-p13.3 113.69–142.24 82867–110103 346.834 0.78259 0.00718*
8 1q31.1-q32 201.58–231.11 185232–210150 347.872 0.77937 0.02791
15 2p12-q22.1 101.56–128.41 79617–119705 341.174 0.79974 0.00694*
18 2q31.1-q34 177.53–206.74 172805–212021 317.985 0.86170 0.03548
20 2q35-qter 233.62–269.07 230618-qter 316.169 0.86603 0.00908
24 3p14.1-q12.3 88.60–117.76 64182–103187 612.921 0.02348 0.80059
31 4p14-q13.3 51.60–78.97 38279–72275 343.939 0.79152 0.00714*
34 4q28.3-q32.1 134.74–159.30 137492–160828 346.992 0.78212 0.01609
43 6pter-p22.3 0.00–32.62 pter-16854 383.747 0.65433 0.03220
44 6p22.3-p21.1 32.62–65.14 16854–43207 592.740 0.03905 0.72593
50 7p21.1-p14.1 29.28–59.93 19430–40230 317.779 0.86218 0.01583
53 7q31.1-q34 122.48–148.11 75216–138638 381.650 0.66230 0.03107
54 7q34-qter 148.11–181.97 138638-qter 313.741 0.87152 0.00536*
55 8pter-p22 0.00–27.40 pter-13111 376.368 0.68196 0.01899
59 8q22-q24.21 110.2–137.92 99237–127416 365.804 0.71999 0.02820
60 8q24.21-qter 137.92–167.90 127416-qter 373.141 0.69378 0.02636
62 9p22.3-p21.1 27.32–53.60 14264–29850 349.926 0.77291 0.03321
68 10p14-q11.21 29.15–62.23 10591–36230 635.659 0.01229 0.79026
75 11p12-q13.3 47.06–72.82 36450–70234 353.473 0.76155 0.02578
79 12pter-p12.1 0.00–24.45 pter-11686 299.278 0.90180 0.00570*
80 12p12.1-p11.21 24.45–53.28 11686–32879 292.228 0.91466 0.00766*
84 12q24.31-qter 139.61–170.60 120806-qter 607.388 0.02714 0.65821
87 13q22.2-q33.1 58.54–85.41 74875–102346 354.469 0.75831 0.04007
89 14pter-q13.1 0.00–40.11 pter- 33529 362.366 0.73182 0.03622
92 14q32.12-qter 105.00-138.18 90647-qter 305.539 0.88932 0.00423*
101 17pter-p12 0.00–25.14 pter-11325 312.768 0.87374 0.00213*
105 18pter-p11 0.00–24.08 pter- 7462 377.842 0.67650 0.04965
113 20pter-p12.3 0.00–21.15 pter-7608 339.111 0.80587 0.00524*
114 20p12.3-p11 21.15–47.52 7608–21259 282.935 0.92982 0.01324
  1. Chromosomal regions with a p(SR) or p(OR) < 0.05 are shown. aBin number from GSMA (1–120 inclusive). bCytogenetic band (Taken from April 2002 Genome Browser, UCSC). cGenetic distance in Marshfield cM (not cumulative). dPhysical position in kilobase pairs (Taken from December 2006 UniSTS, NCBI/Genome Browser, UCSC). *p < 0.000417 = Genome wide significance for linkage, p < 0.0083 = Suggestive for linkage [5].