Skip to main content

Table 7 Adjusted* mean AAT serum levels in women by menopausal status and hormone intake

From: Circulating alpha1-antitrypsin in the general population: Determinants and association with lung function

  Predictor Number of subjects AAT (SE) (g/L) no CRP adjustment AAT (SE) (g/L) CRP adjustment
Menopausal status in women without hormonal treatment¶,†: Premenopausal 806 1.277 (0.007) 1.282 (0.007)
  Postmenopausal 848 1.256 (0.007) 1.252 (0.006)
    p = 0.038 p = 0.003
Oral contraceptives in premenopausal women: no OC use 640 1.278 (0.007) 1.288 (0.007)
  use of OC 166 1.520 (0.016) 1.470 (0.016)
    p < 0.001 p < 0.001
Hormone replacement in postmenopausal women: no use of HRT 324 1.207 (0.015) 1.216 (0.014)
  use of HRT 524 1.272 (0.015) 1.268 (0.014)
    p < 0.001 p < 0.001
  1. * adjusted for BMI, age, active and passive smoking, alcohol consumption, systolic blood pressure and study area perimenopausal women (n = 82) and women with unclear/missing information on hormonal use (n = 243) were excluded; not adjusted for age due to co-linearity between age and menopausal status; OC = oral contraception; HRT = hormone replacement therapy;