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Table 4 Estimated* 10 year change in FVC (mL), FEV1 (mL) and FEV1/FVC (%) across baseline BMI quartiles, overall and among never smokers who did not have asthma at baseline or during the study

From: Longitudinal association of body mass index with lung function: The CARDIA Study

Quartiles of baseline BMI 10-year Change in lung function value
All participants FVC FEV1 FEV1/FVC
<21.2 kg/m2 71 (-43 – 184) 60 (-38 – 159) -0.07% (-1.40% – 1.26%)
21.3–<23.4 kg/m2 19 (-94 – 133) 18 (-79 – 116) 0.29% (-1.03% – 1.62%)
23.4–<26.4 kg/m2 -72 (-186 – 41) -28 (-125 – 70) 1.00% (-0.33% – 2.33%)
≥ 26.4 kg/m2 -185 (-298 – -71) -64 (-161 – 34) 2.03% (0.71% – 3.36%)
p trend <0.0001 <0.0001 <0.0001
Never smoker, never asthma    
<21.2 kg/m2 129 (-37 – 294) 76 (-62 – 215) -0.84% (-2.63% – 0.95%)
21.3–<23.4 kg/m2 78 (-87 – 244) 29 (-109 – 168) -0.60% (-2.39% – 1.18%)
23.4–<26.4 kg/m2 -18 (-184 – 147) -28 (-166 – 111) 0.05% (-1.73% – 1.84%)
≥ 26.4 kg/m2 -138 (-304 – 27) -47 (-186 – 91) 1.60% (-0.19% – 3.39%)
p trend <0.0001 <0.0001 <0.0001
  1. * Estimated FVC, FEV1 and FEV1/FVC were obtained using a repeated measures linear regression model to estimate lung function values over a 10 year period across baseline BMI quartiles after adjusting for current age, (current age)2, race, gender, study center, height, (height)2, baseline age group, smoking status, asthma status, physical activity and alcohol intake all measured at baseline (year 0).