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Table 2

From: Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by Gram-positive and Gram-negative bacteria in human airway smooth muscle cells

Treatments

Concentrations

Mean ± s.e.m

control

0

248.3 ± 76.44

S. aureus (CFU ml-1)

106

328.8 ± 132.1

 

107

170.0 ± 56.09

 

108

2564 ± 1062

PAM 3 (ng ml-1)

3

405.3 ± 103.0

 

30

2108 ± 531.5

 

300

7994 ± 2178.0

FSL1 (ng ml-1)

10

370.6 ± 144.4

 

100

509.0 ± 214.4

 

1000

3792 ± 1379

MDPLys18 (10 nM)

10

218.1 ± 95.11

 

100

444.1 ± 143.1

  1. Effect of Gram-positive bacteria and associated PAMPs on CXCL-8 release from human ASMCs over 48 h. ASMCs were treated either Gram-positive bacteria S. aureus, (106–108 CFU ml-1), Pam3CSK4 (3 – 300 ng ml-1), FSL-1, (10 – 1000 ng ml-1) or MDPLys18 (10 nM and 100 nM). The data represent the mean ± SEM of triplicate of three different donors.