The effect of deep inspirations (DI) on lung compliance (CL) presented as ΔCL. DI attenuated the fall in ΔCL in both healthy mice (PBS'17) and in mice with acute airway inflammation (OVA'98). Mice with chronic airway inflammation, the OVA'98 group, had significantly larger fall in ΔCL than healthy control animals, the PBS'98 group. DI attenuated the fall in ΔCL in both groups, OVA'98 and PBS'98. Values are mean ± SEM, * P < 0.05, ** P < 0.01, *** P < 0.001.