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Table 4 Unadjusted Odds Ratios, multinomial logistic regression, for covariates on wheeze phenotypes

From: IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study

 

Early-transient

Early-onset persistent

Late-onset

Covariate

OR, p-value

OR, p-value

OR, p-value

rs1800925, CT-TT vs CC

0.99, 0.971

0.98, 0.928

0.91, 0.743

rs2066960, CA-AA vs CC

1.61, 0.032

1.36, 0.273

1.24, 0.524

rs1295686, CT-TT vs CC

1.02, 0.922

1.12. 0.642

1.02, 0.937

rs20541, GA-AA vs GG

1.17, 0.393

1.12, 0.614

1.55, 0.096

rs1295685, GG vs GA-AA

1.16, 0.411

1.15, 0.535

1.51, 0.116

others vs CCG/CCG

1.10, 0.592

0.93, 0.729

1.10, 0.709

ETS-2 vs ETS-0

1.70, 0.022

2.93, <0.0001

0.57, 0.173

ETS-1 vs ETS-0

1.57, 0.023

1.86, 0.018

0.61, 0.861

  1. ‡ The reference was the group who never report wheeze up to age 10 (n = 426).
  2. CCG/CCG is the most common haplotype pair constructed based on rs1800925, rs2066960 and rs20541, using PHASE 2.0.2 software [34]. ETS-0, mothers did not smoke during pregnancy and children not exposed to household ETS; ETS-1, mothers did not smoke during pregnancy, but children were exposed to household ETS; ETS-2, mothers smoked during pregnancy and children were exposed to household ETS
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Respiratory Research

ISSN: 1465-993X

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