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Figure 4 | Respiratory Research

Figure 4

From: Remodeling of extra-bronchial lung vasculature following allergic airway inflammation

Figure 4

Significant increase in myofibroblasts numbers following allergen challenge. The number of myofibroblasts (defined as solitary cells co-positive for α-smooth muscle actin and procollagen I) increased significantly following allergen exposure. Occasional smooth muscle cells may produce procollagen I; however smooth muscle cells are not normally solitary. Sporadic myofibroblasts were also visible before allergen challenge, but when correlated to the length of the basement membrane (BM) the values are very small and closed in on zero. The data are given as mean ± SEM and compared against control using the Wilcoxon Signed-ranks test, * indicates p < 0.05.

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