Figure 7
From: Heme oxygenase-1 prevents smoke induced B-cell infiltrates: a role for regulatory T cells?
Foxp3 positive cells in lung tissue. A: Foxp3 positive cells (red nuclear staining) present in lung tissue (100×). B: Foxp3 positive cells expressed as total numbers per mm2 lung tissue after long term smoke exposure and protoporphyrin treatment. Smoke groups are represented by closed symbols and sham smoke groups by open symbols. The significant results of the regression analysis are depicted beneath the figure, as well as a trend for an effect of CoPP treatment. C: Fluorescent double staining for CD3 (green) and Foxp3 (red) in lung (upper panel, 630×) and spleen (lower panel, 400×) showing that Foxp3 specifically stains T cells. The orange cells in the lung are pigmented macrophages, which show auto fluorescence.