| | Mac | Epi | Eos | Neut | Lymph |
|---|
PBS | 0.3 ± 0.08 | 0.5 ± 0.08 | 0 | 0.01 ± 0.003 | 0.005 ± 0.002 |
PBS-Ap | 0.3 ± 0.09 | 0.3 ± 0.06 | 0 | 0.01 ± 0.002 | 0.005 ± 0.002 |
frass | 1.9 ± 0.3 | 0.6 ± 0.1 | 0.4 ± 0.07 | 0.5 ± 0.09 | 0.58 ± 0.05 |
frass-Ap | 1.6 ± 0.2 | 0.9 ± 0.3 | 0.5 ± 0.1 | 0.4 ± 0.08 | 0.7 ± 0.02 |
- Balb/c mice were challenged on day 0, 7, and 14 with PBS, aprotinin-treated PBS (PBS-Ap), GC frass (40 μg/40 μl) or aprotinin-treated GC frass (frass-Ap). On day 17, BAL fluid was harvested and differential cell counts performed. These data represent 6 mice per group and are expressed as mean ± SEM cell number ×104. There were no statistical differences between PBS-Ap and PBS, nor were there differences between GC frass-Ap and GC frass. Statistical significance between GC frass and PBS treatments were determined by ANOVA (mac p < 0.001; eos p = 0.002; neut p < 0.001; lymph p < 0.001).
