PIO inhibits inflammatory responses to CRA challenge as effectively as DEX. PIO, DEX, or vehicle (Veh) was administered daily (days 14–21). All measurements (8 mice/group) were performed 24 h following final CRA challenge. A. Peribronchial inflammatory cell infiltration was visualized by H&E staining. B. Eosinophil infiltration was quantified by counting 100 high-powered fields per lung. C. Total serum IgE levels were measured by ELISA. *P < 0.05 compared to vehicle treatment.