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Table 1 Effect of mAbs on ability of SP-D to inhibit viral hemagglutination activity

From: Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D

MAb added:

None

245-01a

246-04

246-07

HA inhibiting conc. of SP-D

(ng/ml)b

49 ± 14

37 ± 11

55 ± 17

>420

p < 0.001

  1. a Recombinant human SP-D multimers were pre-incubated with the indicated MAbs prior to adding SP-D to virus and assaying HA inhibition.
  2. b The values shown are mean ± SEM (n = 4) amounts of SP-D needed to inhibit 40 HA units of the Phil82 strain of IAV.
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