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Table 2 Diagnosis of COPD and reversibility tests.

From: COPD diagnosis related to different guidelines and spirometry techniques

 

ERS

NICE

GOLD

COPD diagnosis using only FVC (%)

17.6

10.2

14.0

COPD diagnosis using best value of SVC and FVC (%)

21.7

11.7

16.8

Reversibility among subjects with COPD (according to ERS, NICE and GOLD guidelines using the best of SVC and FVC)

N

861

446

652

Percent of predicted (mean; 95%CI)

4.8 (4.4–5.1)

5.5 (5.0–6.0)

3.7 (3.3–4.2)

Percent of pre-bronchodilator (mean; 95%CI)

6.9 (6.3–7.5)

9.2 (8.3–10.1)

6.0 (5.3–6.7)

  1. COPD according to the NICE, GOLD and ERS guidelines in 3887 smokers who were smoking more than 8 cigarettes per day at the time of the trial. The prevalence has been calculated using either FVC or the best of FVC and SVC. Figures in bold indicate the analysis which is recommended in the guidelines, respectively. The table is also showing reversibility after inhalation of 0.8 mg of salbutamol as percent of predicted value and as percent of pre-bronchodilator value.