Glucocorticoid receptor gene polymorphisms associated with progression of lung disease in young patients with cystic fibrosis

Table 2 Genotype frequencies and p-value for Hardy-Weinberg equilibrium (HWE) in the cystic fibrosis patients. The genotype frequencies from previous studies in Caucasians are listed for comparison.

Genotypes	Frequencies in the cystic fibrosis patients (n = 255)	Frequencies in previous studies in Caucasians
*TthIII*		van Rossum et al. [30] (n = 209)
TT	0.09	0.16
CT	0.45	0.44
CC	0.46	0.40
HWE	0.66
*ER22/23EK*		van Rossum et al. [21] (n = 202)
AA	0.004	0
AG	0.026	0.09
GG	0.97	0.91
HWE	0.30
*N363S*		Huizenga et al. [20] (n = 216)
GG	0	0
AG	0.06	0.06
AA	0.94	0.94
HWE	0.61
*BclI*		Rosmond et al. [45] (n = 284)
GG	0.10	0.14
CG	0.45	0.46
CC	0.45	0.40
HWE	0.79

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