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Table 1 Physiological characteristics of study population.

From: Bronchial epithelial spheroids: an alternative culture model to investigate epithelium inflammation-mediated COPD

 

COPD Patients (n = 16)

Non-COPD Smokers (n = 13)

p value

Age, yr

57.5 ± 9.9

56.8 ± 11.1

NS

Sex (M/F)

13/3

11/2

NS

Weight, kg

77.1 ± 23.2

69.1 ± 15.1

NS

Height, m

1.71 ± 0.09

1.71 ± 0.10

NS

BMI, kg/m2

26.03 ± 6.85

23.40 ± 3.84

NS

PostBD-FEV1, %

55.38 ± 13.7

100.77 ± 9.64

<0.01

FVC, %

82.31 ± 12.13

104.45 ± 7.87

<0.01

Post-BD-FEV1/FVC, %

53.06 ± 10.41

77.08 ± 2.96

<0.01

TLC, %

110.56 ± 19.22

97.77 ± 9.42

<0.01

RV, %

155.69 ± 49.63

96.89 ± 28.01

<0.01

KCO, %

69.63 ± 21.07

87.30 ± 10.00

<0.01

Smoking status, Current/Former

8/8

6/7

NS

Pack years of smoking

44.44 ± 15.03

25.92 ± 9.37

<0.05

Moderate/Severe COPD

10/6

-

-

MMRC Dyspnea scale

2.13 ± 0.62

-

-

Distance walked in 6 min, m

339 ± 90

-

-

BODE Index

3.25 ± 2.66

-

-

  1. BD = bronchodilator, BMI = body mass index, F = Female; M = Male; NS = statistically non significant. Values are presented as mean ± SD. Mann-Whitney U-test.