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Table 1 Patient characteristics

From: Smoking cessation and bronchial epithelial remodelling in COPD: a cross-sectional study

 

COPD Current smokers

COPD Ex-smokers

  

combined group

quit < 3.5 yrs

quit ≥3.5 yrs

General

    

Sex (M/F, n)

59/13

40/2 *

20/1

20/1

Age (yrs)

60 ± 8

64 ± 7 *

61 ± 8

67 ± 4 *†

Pack-years (yrs)

43 (32–56)

37 (28–53)

45 (29–65)

35 (26–41) *

Duration of smoking cessation (yrs)

-

3.5 (1–10)

1.0 (1.0–2.0)

10 (6.5–14.5)

Smoking duration (yrs)

44 ± 8

41 ± 10

43 ± 11

39 ± 8

Chronic bronchitis (%)

55.6

31.0 *

23.8 *

38.1

Lung Function

    

Postbronchodilator FEV1 (%pred)

63.3 ± 8.3

62.5 ± 9.6

62.6 ± 10

62.5 ± 9.4

Postbronchodilator FEV1/IVC (%)

49.5 ± 8.5

46.0 ± 8.3 *

45.3 ± 8.6 *

46.7 ± 8.1

ΔFEV1 (%pred)

6.9 ± 5.2

6.8 ± 4.5

6.9 ± 3.9

6.8 ± 5.1

KCO (%pred)

73.3 ± 25.1

80.4 ± 25.9

75.3 ± 24.9

85.7 ± 26.5 *

  1. Data are presented as mean ± standard deviation or median (IQR: 25th – 75th percentile), ex-smokers are divided in two groups based on median duration of smoking cessation (3.5 years). FEV1 = Forced expiratory volume in one second, IVC = Inspiratory vital capacity, ΔFEV1 = Reversibility to salbutamol (change in FEV1 as percentage of predicted), KCO = Diffusing capacity for carbon monoxide per liter alveolar volume, pred = predicted. Patient characteristics have been described before [17].
  2. * p < 0.05: compared to COPD smokers [Chi-square tests for sex differences, 2-tailed unpaired t-tests for other (log-transformed) data]; † p < 0.05: compared to COPD ex-smokers who quit <3.5 yrs (2-tailed unpaired t-tests)
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Respiratory Research

ISSN: 1465-993X

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