Figure 5

Accuracy of bronchial microdialysis of lactate. All values (gray circles) and mean (-) are presented. One value (open circle) is excluded as an outlier due to extreme deviation in the arterial microdialysis value. The accuracy of bronchial microdialysis with a continuous lactate infusion was mean 0.26 ± 0.08 with a coefficient of variation of 62.6%. The accuracy of bronchial microdialysis with a continuous lactate infusion and a correction by the arteriobronchial urea gradient was mean 0.81 ± 0.06 with a coefficient of variation of 17.0%. The reduced coefficient of variation after correction by the arteriobronchial ureagradient sustains the ureacorrection as useful correction factor to estimate the absolute concentrations of molecules in the epithelial lining fluid as measured by microdialysis.