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Figure 3 | Respiratory Research

Figure 3

From: Effect of hypoxia and Beraprost sodium on human pulmonary arterial smooth muscle cell proliferation: the role of p27kip1

Figure 3

Effects of BPS on intracellular cAMP production during hypoxia. Cultured HPASMC were exposed to 21% or 2% oxygen in the presence or absence of 10 μM of BPS for indicated periods. Concentrations of cAMP in cell lysates were measured using low-pH cAMP ELISA kits. Although BPS significantly induced cAMP expression, intracellular cAMP expression did not significantly differ between the indicated oxygen concentrations. Line with solid circles, 21% oxygen; dotted line with open circles, 2% oxygen. Data are expressed as means ± SE (n = 6).

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