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Table 1 Characteristics of study subjects and healthy volunteers

From: Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced bronchoconstriction

Characteristics. Dimension. Patients with EIB. Patients without EIB. Differences between asthma patients with and without EIB. Healthy volunteers.
Number of patients   11 8   7
Sex F/M 7/4 5/3   4/3
Age Years 27.36 ± 7.50 31.63 ± 5.40 p = 0.19 28.40 ± 4.90
Duration of symptoms Years 3.70 ± 4.63 4.12 ± 3.54 p = 0.32  
Baseline FEV1 % predicted 95.63 ± 18.54 92.25 ± 8.61 p = 0.63 106.85 ± 9.73
Maximum decrease in FEV1 after exercise % 25.8 ± 13.5 3.6 ± 1.9 p = 0.0003 0.71 ± 3.2*+
Log PC20hist FEV1 mg/ml -0.59 ± 1.16 -0.05 ± 0.55 p = 0.24  
Blood eosinophil count cells/mm3 239 ± 138 157 ± 66 p = 0.14 51 ± 26*+
Serum total IgE kU/L 358 ± 322 171 ± 69 p = 0.13 65 ± 31*+
Baseline FENO ppB 98.90 ± 55.37 66.62 ± 23.05 p = 0.21 18.00 ± 5.59*+
Baseline ET-1 fmol/ml 0.88 ± 0.24 0.74 ± 0.25 p = 0.29 0.59 ± 0.18*
  1. Data are presented as mean ± SD
  2. FEV1 – forced expiratory volume in one second
  3. PC20histamine FEV1 – provocative concentration of histamine that caused a 20% fall in FEV1
  4. * Values significantly different from patients with EIB, p < 0.05
  5. + Values significantly different from patients without EIB, p < 0.05