Characteristics. | Dimension. | Patients with EIB. | Patients without EIB. | Differences between asthma patients with and without EIB. | Healthy volunteers. |
---|---|---|---|---|---|
Number of patients | Â | 11 | 8 | Â | 7 |
Sex | F/M | 7/4 | 5/3 | Â | 4/3 |
Age | Years | 27.36 ± 7.50 | 31.63 ± 5.40 | p = 0.19 | 28.40 ± 4.90 |
Duration of symptoms | Years | 3.70 ± 4.63 | 4.12 ± 3.54 | p = 0.32 |  |
Baseline FEV1 | % predicted | 95.63 ± 18.54 | 92.25 ± 8.61 | p = 0.63 | 106.85 ± 9.73 |
Maximum decrease in FEV1 after exercise | % | 25.8 ± 13.5 | 3.6 ± 1.9 | p = 0.0003 | 0.71 ± 3.2*+ |
Log PC20hist FEV1 | mg/ml | -0.59 ± 1.16 | -0.05 ± 0.55 | p = 0.24 |  |
Blood eosinophil count | cells/mm3 | 239 ± 138 | 157 ± 66 | p = 0.14 | 51 ± 26*+ |
Serum total IgE | kU/L | 358 ± 322 | 171 ± 69 | p = 0.13 | 65 ± 31*+ |
Baseline FENO | ppB | 98.90 ± 55.37 | 66.62 ± 23.05 | p = 0.21 | 18.00 ± 5.59*+ |
Baseline ET-1 | fmol/ml | 0.88 ± 0.24 | 0.74 ± 0.25 | p = 0.29 | 0.59 ± 0.18* |