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Table 1 Characteristics of study subjects and healthy volunteers

From: Endothelin-1 in exhaled breath condensate of allergic asthma patients with exercise-induced bronchoconstriction

Characteristics.

Dimension.

Patients with EIB.

Patients without EIB.

Differences between asthma patients with and without EIB.

Healthy volunteers.

Number of patients

 

11

8

 

7

Sex

F/M

7/4

5/3

 

4/3

Age

Years

27.36 ± 7.50

31.63 ± 5.40

p = 0.19

28.40 ± 4.90

Duration of symptoms

Years

3.70 ± 4.63

4.12 ± 3.54

p = 0.32

 

Baseline FEV1

% predicted

95.63 ± 18.54

92.25 ± 8.61

p = 0.63

106.85 ± 9.73

Maximum decrease in FEV1 after exercise

%

25.8 ± 13.5

3.6 ± 1.9

p = 0.0003

0.71 ± 3.2*+

Log PC20hist FEV1

mg/ml

-0.59 ± 1.16

-0.05 ± 0.55

p = 0.24

 

Blood eosinophil count

cells/mm3

239 ± 138

157 ± 66

p = 0.14

51 ± 26*+

Serum total IgE

kU/L

358 ± 322

171 ± 69

p = 0.13

65 ± 31*+

Baseline FENO

ppB

98.90 ± 55.37

66.62 ± 23.05

p = 0.21

18.00 ± 5.59*+

Baseline ET-1

fmol/ml

0.88 ± 0.24

0.74 ± 0.25

p = 0.29

0.59 ± 0.18*

  1. Data are presented as mean ± SD
  2. FEV1 – forced expiratory volume in one second
  3. PC20histamine FEV1 – provocative concentration of histamine that caused a 20% fall in FEV1
  4. * Values significantly different from patients with EIB, p < 0.05
  5. + Values significantly different from patients without EIB, p < 0.05