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Table 1 Summary of lectin binding intensities in fetal, paediatric and adult respiratory tissues using Sambucus nigra agglutinin (SNA) and Maackia amurensis 1 and 2 (MAA1 and MAA2).

From: Sialic acid receptor detection in the human respiratory tract: evidence for widespread distribution of potential binding sites for human and avian influenza viruses

 

Fetus (n = 8)

Paediatric lung (n = 12)

Adult NP (n = 8)

Adult bronchus (n = 7)

Adult lung (n = 5)

 

Alv

Bronch

Alv

Bronch

Gland

Epith

Gland

Epith

Gland

Macro

Pneu

Bronch

SNA

- → +

- → +

+

+/-

+

++

++

++

++

+

+

+

MAA1

++ → -

- → +

-

++

+

++

++

++

++

+/++

-

++

MAA2

- → +

+ → -

++

-

+/-

-

-

-

-

-

++

-

  1. Alv = alveolus, Bronch = bronchial epithelium, Epith = epithelium, Macro = macrophage and Pneu = pneumocyte. The arrows in fetal tissue indicate the changes in expression from 20 weeks gestation to term.