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Table 3 Body composition and the risk of self-reported functional limitation among 355 patients with COPD

From: Body composition and functional limitation in COPD

Measure of body composition

Age adjusted

Age, height, FEV1/FVC adjusted

Age, height, FEV1/FVC, race, education, and smoking adjusted

 

OR (95% CI)

OR (95% CI)

OR (95% CI)

MEN (n = 143)

   

Lean/fat ratio

1.02 (0.87 to 1.20)

0.98 (0.82 to 1.16)

0.99 (0.83 to 1.18)

SAD

1.07 (0.99 to 1316)

1.10 (1.0 to 1.20)

1.09 (0.99 to 1.21)

BMI

   

Normal weight

Referent

Referent

Referent

Overweight

0.36 (0.10 to 1.27)

0.42 (0.11 to 1.56)

0.46 (0.12 to 1.81)

Obese

0.92 (0.38 to 2.24)

1.16 (0.44 to 3.03)

1.12 (0.39 to 3.20)

WOMEN (n = 212)

   

Lean/fat ratio

0.49 (0.32 to 0.75)

0.44 (0.27 to 0.70)

0.45 (0.28 to 0.74)

SAD

1.13 (1.06 to 1.21)

1.15 (1.07 to 1.24)

1.15 (1.07 to 1.23)

BMI

   

Normal weight

Referent

Referent

Referent

Overweight

0.79 (0.28 to 2.24)

0.82 (0.28 to 2.37)

0.74 (0.25 to 2.18)

Obese

3.0 (1.45 to 6.23)

3.77 (1.70 to 8.37)

3.50 (1.53 to 8.01)

  1. Results are from separate multivariate logistic regression of self-reported functional limitation regressed on body composition measures plus covariates.
  2. Lean/fat ratio = derived from bioelectrical impedance. Odds ratios are expressed per 0.50 increment in the ratio.
  3. SAD = sagittal abdominal diameter, an estimate of visceral fat. Odds ratios are expressed per 1 cm increment.
  4. BMI = body mass index, an estimate of adiposity; normal weight (18.5 to 24.9 kg/m2) overweight = 25.0 to 29.9 kg/m2, obese = 30.0 kg/m2 or greater; only 9/355 (2.5%) of subjects were in underweight category (< 18.5 kg/m2) so these were included in the normal weight group.