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Table 4 Mean change from baseline in FEV1, and morning and evening PEF after treatment

From: Salmeterol plus fluticasone propionate versus fluticasone propionate plus montelukast: a randomised controlled trial investigating the effects on airway inflammation in asthma

Variable

SFC (n = 33)

FP/M (n = 33)

True treatment difference (95% CI)

 

Baseline (mean)

Change* (mean (95% CI))

Baseline (mean)

Change* (mean (95% CI))

 

FEV1 (L)

2.65

0.41 (0.27, 0.56)

2.76

0.30 (0.16, 0.44)

0.11 (-0.10, 0.32)

Mean Morning PEF (L/min)

411.8

61.9 (48.3, 75.6)

421.5

28.7 (14.7, 42.6)

33.3 (13.6, 52.9)†

Mean Evening PEF (L/min)

438.8

41.7 (28.3, 55.1)

439.3

19.0 (5.3, 32.7)

22.7 (3.4, 42.1)‡

  1. * adjusted mean change from baseline, adjusted for baseline values, age, sex, and height; † between group p = 0.001; ‡ between group p = 0.022
  2. CI, confidence interval; FEV1, forced expiratory volume in 1 second; FP/M, fluticasone propionate plus montelukast; n, number; PEF, peak expiratory flow; SFC, salmeterol plus fluticasone propionate
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