Table 2 Change from baseline in levels of airway inflammatory markers
Marker | SFC (n = 33) | FP/M (n = 33) | Treatment difference (95% CI) | ||
|---|---|---|---|---|---|
Baseline | Change* (95% CI) | Baseline | Change* (95% CI) | ||
Primary markers (median) | |||||
Neutrophils (%) | 37.40 | -2.30 (-16.80, 14.70) | 28.00 | 3.00 (-7.20, 15.50) | -9.40 (-26.50, 6.40) |
Eosinophils (%) | 1.20 | -0.50 (-2.80, 0.80) | 1.00 | -0.50 (-1.00, 0.00) | 0.20 (-1.50, 1.50) |
Lymphocytes (%) | 0.00 | 0.00 (-0.30, 0.50) | 0.00 | 0.00 (0.00, 0.00) | 0.00 (-0.30, 0.50) |
Macrophages (%) | 45.40 | 4.00 (-10.70, 15.20) | 64.00 | -0.50 (-8.70, 10.80) | 1.70 (-12.60, 17.20) |
Epithelial cells (%) | 3.40 | 0.00 (-4.30, 8.00) | 6.00 | 0.00 (-3.50, 2.50) | 2.20 (-2.80, 9.00) |
Secondary marker (median) | |||||
IL-8 (ng/ml) | 3.80 | 0.00 (-0.29, 5.55) | 2.99 | 0.00 (-5.32, 1.11) | 3.85 (-0.32, 8.08) |