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Table 7 Association between plasma markers and % DLCO, adjusted*

From: Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study

Analyte

β†

95% CI

p‡

CCL2/MCP-1

-0.001

-0.01, 0.003

0.58

CCL4/MIP-1β

0.004

-0.02, 0.03

0.76

CCL5/RANTES

-0.01

-0.03, 0.003

0.11

CCL11/eotaxin

-0.005

-0.01, 0.002

0.15

CXCL8/IL-8

-0.004

-0.01, 0.002

0.18

CXCL9/Mig

-0.02

-0.03, -0.002

0.02

EGF

-0.01

-0.03, 0.01

0.29

Fas

0.01

0.003, 0.02

0.01

G-CSF

-0.01

-0.02, -0.0001

0.05

HGF

-0.0001

-0.01, 0.01

0.99

IFN-γ

-0.02

-0.05, 0.01

0.11

IL-2

-0.03

-0.06, 0.01

0.11

IL-2R

0.01

-0.01, 0.02

0.46

IL-4

-0.02

-0.05, 0.02

0.30

IL-13

-0.02

-0.03, -0.002

0.03

TNF-α

-0.01

-0.03, 0.003

0.11

  1. *Adjusted for % FEV1, current smoking, pack years, ICS use, SCS use, statin use, gender and age.
  2. †β = regression co-efficient
  3. ‡p = p-value