Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study

Table 4 Association between plasma marker concentrations and % FEV1, unadjusted

Classification	Plasma marker	β^†	95% CI	p^‡
Apoptosis	Fas	0.003	-0.001, 0.01	0.12
	FasL	0.001	-0.004, 0.01	0.67
Acute phase	CRP	-0.01	-0.02, 0.003	0.19
	MPO	0.0004	-0.01, 0.01	0.93
Chemokines	CCL2/MCP -1	-0.002	-0.004, 0.001	0.14
	CCL3/MIP-1α	-0.004	-0.02, 0.01	0.53
	CCL4/MIP-1β	-0.01	-0.02, -0.003	< 0.01
	CCL5/RANTES	-0.005	-0.01, 0.002	0.18
	CCL11/eotaxin	-0.003	-0.006, 0.0004	0.09
	CXCL8/IL-8	-0.002	-0.01, 0.001	0.18
	CXCL9/Mig	-0.01	-0.01, 0.001	0.09
T _H Related Cytokines	IFN-γ	-0.01	-0.03, -0.001	0.04
	IL-2	-0.02	-0.04, -0.002	0.03
	IL-2R^§	-0.005	-0.01, 0.0003	0.06
	IL-4	-0.02	-0.03, -0.003	0.02
	IL-13	-0.01	-0.02, -0.0004	0.04
Inflammation	TNF-α	-0.01	-0.02, 0.002	0.11
	TNFRI^§	-0.001	-0.01, 0.004	0.72
	TNFRII^§	-0.001	-0.01, 0.004	0.83
	IL-1β	-0.01	-0.02, 0.01	0.47
	IL-6	-0.003	-0.01, 0.01	0.61
	IL-10	-0.001	-0.01, 0.004	NE*
Growth Factors	EGF	-0.01	-0.01, 0.001	0.09
	EGFR^§	0.001	-0.001, 0.003	0.25
	FGFβ	NE*	NE*	NE*
	G-CSF	-0.003	-0.01, 0.002	0.28
	HGF	-0.002	-0.01, 0.001	0.20
	VEGF	NE*	NE*	NE*

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