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Table 1 Detectability of plasma marker concentrations

From: Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study

Classification

Plasma marker

Mean (pg/mL) + SE

LLD* (pg/mL)

below LLD (%)

Apoptosis

Fas

74 ± 3

1.3

0

 

FasL

68 ± 4

6.5

0

Acute phase

CRP

6268332 ± 1124813

78

0

 

MPO

4381 ± 589

13

3

Chemokines

CCL2/MCP -1

202 ± 6

10

0

 

CCL3/MIP-1α

161 ± 33

6.8

5

 

CCL4/MIP-1β

115 ± 20

1.3

1

 

CCL5/RANTES

5249 ± 398

8.2

0

 

CCL11/eotaxin

76 ± 3

2.3

0

 

CXCL8/IL-8

11 ± 0.4

6.1

0

 

CXCL9/Mig

1163 ± 87

35

0

T H Related Cytokines

IFN-γ

55 ± 7

2.1

8

 

IL-2

103 ± 23

2.6

23

 

IL-2R†

344 ± 28

39

0

 

IL-4

15 ± 3

0.6

25

 

IL-13

98 ± 7

8.2

11

Inflammation

TNF-α

55 ± 7

5.3

0

 

TNFRI†

1352 ± 95

36

0

 

TNFRII†

3231 ± 138

39

0

 

IL-1β

72 ± 17

8.5

45

 

IL-6

19 ± 4

0.4

1

 

IL-10

0.3 ± 0.08

0.2

96

Growth Factors

EGF

19 ± 1.5

2.5

0

 

EGFR†

19769 ± 434

13.5

0

 

FGFβ

NE‡

NE‡

NE‡

 

G-CSF

2496 ± 180

379

0

 

HGF

196 ± 9

2.8

0

 

VEGF

NE‡

NE‡

NE‡

  1. *LLD, Lower Limit of Detection
  2. †For clarity, the soluble receptors are grouped with their respective ligand
  3. ‡NE, Not Evaluable