From: Perforin, granzyme B, and FasL expression by peripheral blood T lymphocytes in emphysema
Variables | Normal non-smokers n = 10 | Normal smokers n = 10 | Emphysematous smokers n = 9 |
---|---|---|---|
Age, yr | 62 ± 2 | 58 ± 1 | 60 ± 1 |
Gender, F/M | 3/7 | 2/8 | 2/7 |
FEV 1 , % predicted | 112.2 ± 4.6 | 111.1 ± 4.1 | 39.6 ± 5.0* |
FEV 1 /FVC | 95.6 ± 1.8 | 94.0 ± 5.8 | 44.6 ± 3.5* |
GOLD stage I/II/III/IV | - | - | 0/2/5/2 |
DLCO, % predicted | - | - | 53.4 ± 17.3 |
Smoking history, pack-years | - | 43 ± 4 | 70 ± 8* |
BMI (kg/m 2 ) | 26.5 ± 1.1 | 27.0 ± 1.6 | 22.2 ± 0.6* |
Presence of emphysema**, subjects | - | - | 9 |