From: Impaired cortical processing of inspiratory loads in children with chronic respiratory defects
Controls n = 11 | P (controls vs pooled patients) | Patients with asthma n = 21 | Patients with cystic fibrosis n = 32 | Patients with neuromuscular disease n = 16 | P (between the patient groups) | |
---|---|---|---|---|---|---|
Male/Female | 5/6 | NS | 12/9 | 16/16 | 12/4 | NS |
Age (years) | 12 ± 3 | NS | 12 ± 3 | 13 ± 4 | 12 ± 3 | NS |
Weight (kg) | 51 ± 12 | 0.008 | 40 ± 13 | 37 ± 11# | 44 ± 7 | < 0.001 |
Height (cm) | 158 ± 18 | 0.006 | 144 ± 15 | 145 ± 18 | 146 ± 19 | NS |
FVC (% Pred) | NP | NP | 98 ± 15§ | 67 ± 26 | 52 ± 22 | < 0.0001 |
FEV1 (% Pred) | NP | NP | 92 ± 16§ | 56 ± 28 | 57 ± 25 | < 0.0001 |
FRC He (% Pred) | NP | NP | 105 ± 20 | 98 ± 24 | 82 ± 32 | NS |
FRC Pl (% Pred) | NP | NP | 125 ± 20 | 165 ± 40 | NP | < 0.05 |
SpO2 (%) | NP | NP | 97 ± 2 | 94 ± 3 | 98 ± 1 | NS |
Rsint (% Pred) | NP | NP | 160 ± 21 | 217 ± 85 | 183 ± 60 | NS |