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Figure 5 | Respiratory Research

Figure 5

From: Protective role of vascular endothelial growth factor in endotoxin-induced acute lung injury in mice

Figure 5

Effect of VEGF on endothelial cell apoptosis assessed by active caspase-3 in cell lysates. a) Stimulation with 100 ng/ml TNF-α stimulation for 4 and 24 h increased the levels of active caspase-3. *p < 0.0001 vs control; p < 0.01 vs control. b) LPS stimulation for 4, 8 and 24 h. Higher concentration (100 ng/ml) of LPS significantly increased active caspase-3 at 8 h and 24 h. *p < 0.0001 vs control. c) VEGF significantly reduced the levels of TNF-α-induced active caspase-3. *p < 0.0001 vs control; p < 0.0001 vs TNF-α. d) VEGF significantly decreased the levels of LPS-induced active caspase-3. *p < 0.0001 vs control; p < 0.0001 vs LPS. n = 4 in each group.

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