Table 1 Characteristics of NETT Genetics Ancillary Study subjects who underwent lung volume reduction surgery (LVRS). N = 203 unless otherwise noted
From: Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery
Characteristic | Mean (SD) or N(%) |
Baseline (pre-randomization) | |
Age, years | 67.5 (6.2) |
Male sex | 123 (60.6%) |
Pack-years of smoking | 65.2 (29.6) |
Upper lobe predominant emphysema | 143 (70.4%) |
Low exercise capacity | 82 (40.4%) |
Modified BODE score | 4.7 (1.6) |
Post-bronchodilator FEV1, liters | 0.80 (0.26) |
Post-bronchodilator FEV1, % predicted | 28.2 (7.5) |
Maximum work achieved on CPET, watts | 41.8 (21.9) |
UCSD shortness of breath questionnaire | 58.7 (17.5) |
Change at 6 months post-LVRS | Â |
Modified BODE score (N = 195) | -1.3 (1.7) |
Post-bronchodilator FEV1, liters (N = 200) | 0.23 (0.26) |
Post-bronchodilator FEV1, % predicted (N = 200) | 8.9 (9.8) |
Maximum work achieved on CPET, watts (N = 198) | 6.4 (14.1) |
UCSD shortness of breath questionnaire (N = 202) | -18.7 (20.7) |