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Table 1 Effects of hypoxia on cardiorespiratory parameters and PB-EPCs

From: Effects of simulated altitude (normobaric hypoxia) on cardiorespiratory parameters and circulating endothelial precursors in healthy subjects

  T0 T1 T2 ΔT0-T1% T0 vs T1 p T1 vs T2 p
FiO2, % 20.9 ± 0.5 11.8 ± 0.9 21.2 ± 0.5 - 43.2 ± 5.3 < 0.0001 < 0.0001
PAO2, mmHg 104.5 ± 14.9 30.2 ± 14.0 99.8 ± 15.8 - 71.8 ± 13.4 < 0.0001 < 0.0001
SpO2, % 97.5 ± 1.4 86.8 ± 4.7 96.9 ± 05 - 10.9 ± 5.0 0.0005 0.0005
RF, breaths/min 16.0 ± 2.9 14.4 ± 3.4 15.8 ± 3.0 - 8.3 ± 21.6 0.235 0.118
Vt, L 0.57 ± 0.09 0.56 ± 0.26 0.6 ± 0.2 - 2.2 ± 43.6 0.937 0.426
HR, beats/min 64.0 ± 8.8 77.4 ± 10.8 66.6 ± 10.3 + 20.9 ± 4.3 < 0.0001 0.002
SBP, mmHg 124.7 ± 4.9 120.3 ± 8.6 122.0 ± 9.0 - 3.5 ± 4.7 0.072 0.645
DBP, mmHg 71.1 ± 3.1 73.0 ± 5.6 76.3 ± 8.2 + 2.7 ± 8.6 0.418 0.116
PB-EPCs, cells/μL 0.38 ± 0.56 0.65 ± 0.72 0.14 ± 0.20 + 237.1 ± 264.5 0.016 0.0491
  1. PB-EPCs, peripheral blood endothelial precursors cells; T0. baseline; T1, after 1h of standardized hypoxia; T2, 7 days after hypoxia; FiO2, Inspiratory Fraction of Oxygen ; PAO2, Alveolar Oxygen Partial Pressure; SpO2, Spot Oxygen Saturation; RF, Respiratory Frequency; Vt, Tidal Volume; HR; Heart Rate; SBP, Systolic Blood Pressure; DBP, Diastolic Blood Pressure.
  2. Values are expressed as means ± SD. A p value < 0.05 was considered significant.