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Figure 2 | Respiratory Research

Figure 2

From: Assessment of pulmonary antibodies with induced sputum and bronchoalveolar lavage induced by nasal vaccination against Pseudomonas aeruginosa: a clinical phase I/II study

Figure 2

Sequential analysis of OprF-OprI-specific IgG and IgA antibodies in single fractions of bronchoalveolar lavage fluid (BALF, A and C) and induced sputum (IS, B and D) of n = 12 healthy volunteers vaccinated with nasal primary and a nasal or systemic booster vaccination. Specimen were obtained 4 weeks after the booster vaccination. The upper panel shows the antibody levels in ELISA units, the lower panel the ratio of the IgG to the IgA levels. Data are given as values (circles) and standard error of the mean (SEM, lines). Antibody composition changed significantly between the first 2 and the consecutive samples in BAL, while it remained stable in all fractions in IS. Mean values of ratios were compared by two-sided paired t-test. A p-value of less than 0.05 was considered significant. * indicate significant differences to the first 2 fractions.

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Respiratory Research

ISSN: 1465-993X

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