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Table 1 Clinical characteristics and lung function parameters of study subjects

From: Vascular endothelial growth factor: an angiogenic factor reflecting airway inflammation in healthy smokers and in patients with bronchitis type of chronic obstructive pulmonary disease?

No

Healthy non-smokers 16

Asymptomatic smokers 17

COPD smokers n = 14

Age (years)

46 ± 11

47 ± 8

54 ± 9

Smoking (pack-years)

0

34 ± 6

45 ± 17

FEV1 (% pred)

106 ± 12*

101 ± 9*

68 ± 11

FVC (% pred)

107 ± 10*

108 ± 11*

85 ± 15

FEV1/FVC (%)

85 ± 6*

79 ± 6*

64 ± 5

FEF25–75 (% pred)

94 ± 31*

79 ± 20*

32 ± 10

RV (% pred)

99 ± 13

92 ± 9

85 ± 25

TLC (% pred)

97 ± 8

96 ± 8

89 ± 12

FRC (% pred)

98 ± 16

95 ± 14

95 ± 15

DLCO (% pred)

91 ± 9

85 ± 10

89 ± 11

PaO2 (mm Hg)

-

96 ± 11

81 ± 14

  1. Values are expressed as mean ± SD.
  2. COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; FEF25–75: forced expiratory flow 25–75; RV: residual volume; TLC: total lung capacity; FRC: forced residual capacity; DLCO: diffusing lung capacity for carbon monoxide; PaO2: partial pressure of oxygen, arterial.
  3. *p < 0.05, asymptomatic smokers and healthy non-smokers vs COPD smokers