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Table 1 Percentage of NHBE cells with specified patterns of TGFα/ADAM17 expression following IL-13 stimulation.

From: IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17

  

EXPRESSION PATTERN

Time point

 

% Cells with Apical TGFα

% Cells with Apical ADAM17

15 min

CON

19

81

 

IL-13

20

80

30 min

CON

18

82

 

IL-13

46

54

60 min

CON

29

71

 

IL-13

35

65

4 hrs

CON

12

88

 

IL-13

2

98

  1. Cells were examined by confocal microscopy to determine whether expression of TGFα or ADAM17 was greater in the apical-most, middle and basal-most sections of the Z-stack images. "Expression pattern" refers to expression noted within [apical/middle/basal] regions on an NHBE cell. "Apical TGFα " refers to a pattern of [TGFα/TGFα/ADAM17]. "Apical ADAM17" refers to a pattern of [ADAM17/ADAM17/TGFα].