Figure 6

Summary of TGFα and ADAM17 expression patterns induced by IL-13. a) Confocal images (y-z plane; apical to basal cross-section) of NHBE cells exposed for 60 min to media alone (control) or IL-13 (10 ng/ml). See Additional files 1 and 2 for movies of Z-stack images (basal to apical) taken from a control culture and an IL-13-treated culture, respectively, at this time point. TGFα (red) and ADAM17 (green); scale bars represent 10 μm. b) Illustration summarizing expression patterns of TGFα and ADAM17 observed via confocal microscopy in IL-13-treated NHBE cells at the times indicated. Colors represent TGFα (red) and ADAM17 (green).