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Table 1 Effects of short-term cultivation upon expression of Ki-67 antigen and of cleaved caspase-3 expression in human NSCLC specimens of both adenocarcinoma and squamous cell carcinoma type. Data are expressed as mean values of percentages ± SEM.

From: A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy

Ki-67

Tissue Type

 

16 h Culture

P-Value

Number of Tested Samples

  

NAT TU

RPMI

  
 

AC

29.2 ± 3.3

18.7 ± 2.5

0.035

N = 20

 

SCC

41.7 ± 4.1

27.4 ± 2.5

0.009

N = 19

Caspase-3

     
 

AC

12.0 ± 2.9

11.1 ± 2.7

0.87

N = 18

 

SCC

9.2 ± 4.3 (median = 2.5)

8.6 ± 1.3 (median = 7.5)

0.018

N = 17

  1. AC : adenocarcinomas ; SCC : squamous cell carcinomas
  2. NAT TU: native tumour (without cultivation); RPMI: cultivated tissues in medium