Figure 4
From: A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy
Transcription of caspase-3 in four different human NSCLC tissue specimens (n = 3 SCC; n = 1 AC) and one human SCLC (small-cell lung cancer) tissue sample in the absence (RPMI) or presence of carboplatin (CARB), vinorelbine (VIN) and gemcitabine (GEM), respectively. Signals of caspase-3 were normalized to the respective GAPDH signals and the resulting values of the untreated medium control tissues (RPMI) were set 100%. The data are shown for each individual specimen separately and are expressed as mean values ± SEM (n = 2). Lines were drawn through all data points derived from a single specimen to better reveal the individual trend of response.