| Azithromycin Group (n = 14) | Placebo Group (n = 12) | p-value |
---|---|---|---|
Incidence of BPD-no. (%) | 9 (64.3) | 10 (83.3) | 0.26 |
Duration of Mechanical Ventilation-median (range) | 13 (1–47) | 35 (1–112) | 0.02 |
Postnatal-steroid | 3 (18.8) | 8 (66.7) | 0.02 |
Days of CPAP (range) | 8 ± 7 | 8 ± 6 | 0.98 |
Grade III or IV IVH-no. (%) | 2 (14) | 2 (16) | 0.86 |
PVL on HUS-no. (%) | 1 (7) | 2 (16) | 0.58 |
Abnormal Transaminases (AST) | 0 | 1 (8) | 0.46 |
Bilirubin Peak | 6.9 ± 1.8 | 6.4 ± 2.1 | 0.54 |
Days to full feeds‡ | 17 ± 5 | 18 ± 4 | 0.76 |
Feeding intolerance*-no. (%) | 4 (29) | 7 (58) | 0.12 |
Necrotizing Enterocolitis-no. (%) | 0 | 1 (8) | 0.46 |
Abnormal hearing screen-no. (%) | 0 | 3 (25) | 0.08 |
Bacterial Infection: | Â | Â | Â |
Blood-no. (%) | 8 (57) | 5 (42) | 0.43 |
Urine-no. (%) | 0 | 3 (25) | 0.08 |
CSF-no. (%) | 0 | 2 (17) | 0.20 |
Fungal Infection: | Â | Â | Â |
Blood-no. (%) | 2 (14) | 1 (8) | 1.0 |
Urine-no. (%) | 0 | 1 (8) | 0.46 |
CSF-no. (%) | 1 (7) | 0 | 1.0 |
Days of Antibiotics§ | 12 ± 11 | 24 ± 23 | 0.09 |
Caffeine Therapy-no. (%) | 13 (92) | 10 (83) | 0.58 |
PDA†-no. (%) | 7 (50) | 9 (75.0) | 0.18 |
Indomethacin¥ |  |  |  |
Median | 1 | 1 | 0.48 |
Interquartile range | 0–1 | 0–2 |  |
PDA ligated-no. (%) | 3 (21) | 3 (25) | 0.82 |
Diuretics-no. (%) | 5 (35) | 7 (58) | 0.24 |
Days of Diuretics | 12 ± 25 | 28 ± 42 | 0.23 |
Bronchodilators-no. (%) | 4 (28) | 8 (67) | 0.05 |
Days of Bronchodilators | 7 ± 15 | 24 ± 25 | 0.04 |
Hospital days | 77 ± 15 | 101 ± 32 | 0.02 |