| Azithromycin Group (n = 19) | Placebo Group (n = 16) | p-value |
---|---|---|---|
Mortality-no. (%) | 5 (26.3) | 4 (25) | 0.9 |
Incidence of BPD-no. (%) | 9 (64.3) | 10 (83.3) | 0.26 |
Duration of Mechanical Ventilation-median (range) | 10 (1–145) | 16 (1–112) | 0.40 |
Postnatal-steroid | 6 (31.5) | 10 (62.5) | 0.05 |
Days of CPAP (range) | 6 ± 7 | 6 ± 6 | 0.84 |
Grade III or IV IVH-no. (%) | 5 (26) | 5 (33) | 0.65 |
PVL on HUS-no. (%) | 1 (5) | 3 (19) | 0.20 |
Abnormal Transaminases (AST) | 0 | 1 | 0.20 |
Bilirubin Peak | 6.5 ± 2 | 6.3 ± 1.9 | 0.68 |
Days to full feeds‡ | 18 ± 5 | 18 ± 54 | 0.95 |
Feeding intolerance*-no. (%) | 5 (26) | 9 (56) | 0.07 |
Necrotizing Enterocolitis-no. (%) | 0 | 1 (6) | 0.20 |
Abnormal hearing screen-no. (%) | 0 | 3 (25) | 0.08 |
Bacterial Infection: | Â | Â | Â |
Blood-no. (%) | 10 (52) | 6 (38) | 0.35 |
Urine-no. (%) | 1 (5) | 4 (25) | 0.15 |
CSF-no. (%) | 0 | 2 (12) | 0.20 |
Fungal Infection: | Â | Â | Â |
Blood-no. (%) | 3 (16) | 2 (12) | 0.78 |
Urine-no. (%) | 0 | 2 (12) | 0.20 |
CSF-no. (%) | 1 (5) | 0 | 1 |
Days of Antibiotics§ | 10 ± 10 | 19 ± 21 | 0.10 |
Caffeine Therapy-no. (%) | 13 (68) | 10 (62) | 0.71 |
PDA†-no. (%) | 10 (52) | 12 (75) | 0.16 |
Courses of indomethacin | Â | Â | 0.49 |
Median | 1 | 1 | Â |
Interquartile range | 0–1 | 0–2 |  |
PDA ligated-no. (%) | 3 (15) | 4 (25) | 0.49 |
Diuretics-no. (%) | 6 (31) | 8 (50) | 0.26 |
Days of Diuretics | 14 ± 30 | 21 ± 38 | 0.53 |
Bronchodilators-no. (%) | 5 (26) | 8 (50) | 0.14 |
Days of Bronchodilators | 10 ± 25 | 18 ± 24 | 0.34 |
Hospital days | 67 ± 40 | 78 ± 50 | 0.47 |